GeneSet AKT phosphorylates targets in the cytosol (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
--- -2.4 0.03496 10.0 4.0 1.22
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000204673 AKT1S1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000124762 CDKN1A oo-
ENSG00000111276 CDKN1B +o+
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000105723 GSK3A ---
ENSG00000082701 GSK3B -o-
ENSG00000135679 MDM2 -o-
ENSG00000103197 TSC2 ---