GeneSet GRB2:SOS provides linkage to MAPK signaling for Intergrins (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
NonAssociatedWithProgression -2.7 0.02536 7.0 5.0 1.9
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000077420 APBB1IP NonAssociatedWithProgression
ENSG00000115414 FN1 o++a
ENSG00000177885 GRB2 NonAssociatedWithProgression
ENSG00000116473 RAP1A NonAssociatedWithProgression
ENSG00000127314 RAP1B NonAssociatedWithProgression
ENSG00000115904 SOS1 -+o
ENSG00000137076 TLN1 NonAssociatedWithProgression