GeneSet Interleukin-1 signaling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.5 0.03235 23.0 4.0 1.05
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000166167 BTRC --o
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000055130 CUL1 o++a
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000196083 IL1RAP o+o
ENSG00000184216 IRAK1 o--a
ENSG00000198001 IRAK4 o--a
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000065559 MAP2K4 NonAssociatedWithProgression
ENSG00000198909 MAP3K3 o-+
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000107968 MAP3K8 o++a
ENSG00000172936 MYD88 +o+
ENSG00000109320 NFKB1 o++a
ENSG00000106100 NOD1 o-+
ENSG00000197329 PELI1 NonAssociatedWithProgression
ENSG00000139946 PELI2 +oo
ENSG00000100387 RBX1 o--a
ENSG00000104312 RIPK2 o++b
ENSG00000113558 SKP1 ---
ENSG00000161011 SQSTM1 ---
ENSG00000055208 TAB2 o--b
ENSG00000157625 TAB3 o+o
ENSG00000168884 TNIP2 o--b
ENSG00000078902 TOLLIP o-o
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000177889 UBE2N o--a
ENSG00000244687 UBE2V1 oo-