GeneSet KEGG_MELANOMA (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.7 0.0349 26.0 9.0 3.69
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000078061 ARAF o--a
ENSG00000157764 BRAF oo-
ENSG00000135446 CDK4 o--a
ENSG00000105810 CDK6 o--a
ENSG00000124762 CDKN1A oo-
ENSG00000101412 E2F1 o--b
ENSG00000007968 E2F2 o--a
ENSG00000112242 E2F3 NonAssociatedWithProgression
ENSG00000077782 FGFR1 o++a
ENSG00000174775 HRAS o--b
ENSG00000140443 IGF1R o++b
ENSG00000133703 KRAS o+o
ENSG00000169032 MAP2K1 NonAssociatedWithProgression
ENSG00000126934 MAP2K2 o--a
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000102882 MAPK3 o--b
ENSG00000135679 MDM2 -o-
ENSG00000187098 MITF o--b
ENSG00000213281 NRAS o--b
ENSG00000121879 PIK3CA +-o
ENSG00000051382 PIK3CB -o-
ENSG00000171608 PIK3CD o++a
ENSG00000105851 PIK3CG o++b
ENSG00000145675 PIK3R1 o--a
ENSG00000105647 PIK3R2 o--a
ENSG00000117461 PIK3R3 NonAssociatedWithProgression
ENSG00000171862 PTEN NonAssociatedWithProgression
ENSG00000132155 RAF1 NonAssociatedWithProgression
ENSG00000139687 RB1 NonAssociatedWithProgression
ENSG00000141510 TP53 o--a