GeneSet KEGG_MTOR_SIGNALING_PATHWAY (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.4 0.04813 33.0 10.0 4.69
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000142208 AKT1 ---
ENSG00000105221 AKT2 o--a
ENSG00000117020 AKT3 o++b
ENSG00000157764 BRAF oo-
ENSG00000135932 CAB39 +o+
ENSG00000102547 CAB39L -+o
ENSG00000168209 DDIT4 o+-
ENSG00000063046 EIF4B o--a
ENSG00000135930 EIF4E2 o--a
ENSG00000187840 EIF4EBP1 o--b
ENSG00000100644 HIF1A NonAssociatedWithProgression
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000102882 MAPK3 o--b
ENSG00000167965 MLST8 o--a
ENSG00000198793 MTOR NonAssociatedWithProgression
ENSG00000140992 PDPK1 -o-
ENSG00000121879 PIK3CA +-o
ENSG00000051382 PIK3CB -o-
ENSG00000171608 PIK3CD o++a
ENSG00000105851 PIK3CG o++b
ENSG00000145675 PIK3R1 o--a
ENSG00000105647 PIK3R2 o--a
ENSG00000117461 PIK3R3 NonAssociatedWithProgression
ENSG00000132356 PRKAA1 -o-
ENSG00000162409 PRKAA2 o++a
ENSG00000106615 RHEB NonAssociatedWithProgression
ENSG00000164327 RICTOR o--b
ENSG00000137154 RPS6 o--a
ENSG00000117676 RPS6KA1 --o
ENSG00000177189 RPS6KA3 NonAssociatedWithProgression
ENSG00000108443 RPS6KB1 NonAssociatedWithProgression
ENSG00000175634 RPS6KB2 -o-
ENSG00000141564 RPTOR o--a
ENSG00000118046 STK11 o--a
ENSG00000125695 STRADA ---
ENSG00000165699 TSC1 NonAssociatedWithProgression
ENSG00000103197 TSC2 ---
ENSG00000177169 ULK1 o--b
ENSG00000140474 ULK3 o--a
ENSG00000112715 VEGFA +-o
ENSG00000173511 VEGFB o--b