GeneSet KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY (Pathways_-_KEGGBioCarta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.4 0.0481 24.0 4.0 1.1
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000110330 BIRC2 NonAssociatedWithProgression
ENSG00000023445 BIRC3 o++a
ENSG00000105483 CARD8 o++a
ENSG00000064012 CASP8 +-o
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000112851 ERBB2IP NonAssociatedWithProgression
ENSG00000080824 HSP90AA1 NonAssociatedWithProgression
ENSG00000096384 HSP90AB1 o--b
ENSG00000166598 HSP90B1 NonAssociatedWithProgression
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000100030 MAPK1 NonAssociatedWithProgression
ENSG00000112062 MAPK14 o++b
ENSG00000102882 MAPK3 o--b
ENSG00000107643 MAPK8 o+o
ENSG00000050748 MAPK9 -o-
ENSG00000249437 NAIP o+o
ENSG00000109320 NFKB1 o++a
ENSG00000100906 NFKBIA o-o
ENSG00000104825 NFKBIB ---
ENSG00000091592 NLRP1 o-+
ENSG00000106100 NOD1 o-+
ENSG00000103490 PYCARD o--a
ENSG00000173039 RELA o--a
ENSG00000104312 RIPK2 o++b
ENSG00000165416 SUGT1 -+o
ENSG00000055208 TAB2 o--b
ENSG00000157625 TAB3 o+o
ENSG00000118503 TNFAIP3 o--a
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000101966 XIAP o+-