GeneSet NOD1/2 Signaling Pathway (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.2 0.04483 17.0 3.0 0.78
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000110330 BIRC2 NonAssociatedWithProgression
ENSG00000023445 BIRC3 o++a
ENSG00000106144 CASP2 o--a
ENSG00000196954 CASP4 o++a
ENSG00000064012 CASP8 +-o
ENSG00000213341 CHUK NonAssociatedWithProgression
ENSG00000083799 CYLD o--b
ENSG00000104365 IKBKB o++a
ENSG00000073009 IKBKG --o
ENSG00000184216 IRAK1 o--a
ENSG00000078747 ITCH o++b
ENSG00000135341 MAP3K7 NonAssociatedWithProgression
ENSG00000112062 MAPK14 o++b
ENSG00000106100 NOD1 o-+
ENSG00000104312 RIPK2 o++b
ENSG00000055208 TAB2 o--b
ENSG00000157625 TAB3 o+o
ENSG00000118503 TNFAIP3 o--a
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000177889 UBE2N o--a
ENSG00000244687 UBE2V1 oo-