GeneSet PD-1 signaling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--b -2.4 0.035 6.0 3.0 0.83
DownRegulated -1.7976931348623157E308 0.0 6.0 6.0 3.54
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000198821 CD247 NonAssociatedWithProgression
ENSG00000167286 CD3D NonAssociatedWithProgression
ENSG00000198851 CD3E o--a
ENSG00000160654 CD3G ---
ENSG00000010610 CD4 o--b
ENSG00000103653 CSK o--b
ENSG00000182866 LCK o-o
ENSG00000179295 PTPN11 NonAssociatedWithProgression
ENSG00000211889 TRAC o--b