GeneSet Platelet degranulation (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o++a -2.3 0.03787 25.0 4.0 1.15
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000125257 ABCC4 o++a
ENSG00000072110 ACTN1 -+o
ENSG00000149925 ALDOA o--b
ENSG00000142192 APP o++b
ENSG00000096070 BRPF3 o-+
ENSG00000198668 CALM1 NonAssociatedWithProgression
ENSG00000128595 CALU o--b
ENSG00000131236 CAP1 o--a
ENSG00000135404 CD63 o--a
ENSG00000010278 CD9 o-o
ENSG00000197766 CFD ---
ENSG00000172757 CFL1 o-o
ENSG00000120885 CLU o++a
ENSG00000185010 F8 o++b
ENSG00000196924 FLNA ---
ENSG00000115414 FN1 o++a
ENSG00000005893 LAMP2 o-+
ENSG00000108518 PFN1 o-o
ENSG00000122194 PLG o+o
ENSG00000196262 PPIA NonAssociatedWithProgression
ENSG00000197746 PSAP oo-
ENSG00000106366 SERPINE1 o+-
ENSG00000142168 SOD1 NonAssociatedWithProgression
ENSG00000122862 SRGN NonAssociatedWithProgression
ENSG00000105329 TGFB1 o--a
ENSG00000102265 TIMP1 o--a
ENSG00000137076 TLN1 NonAssociatedWithProgression
ENSG00000205542 TMSB4X NonAssociatedWithProgression
ENSG00000127824 TUBA4A NonAssociatedWithProgression
ENSG00000035403 VCL o++a
ENSG00000112715 VEGFA +-o
ENSG00000173511 VEGFB o--b
ENSG00000071127 WDR1 NonAssociatedWithProgression