GeneSet TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Pathways_-_Reactome.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -2.3 0.03737 6.0 3.0 0.85
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000184216 IRAK1 o--a
ENSG00000198001 IRAK4 o--a
ENSG00000185507 IRF7 ---
ENSG00000172936 MYD88 +o+
ENSG00000175104 TRAF6 NonAssociatedWithProgression
ENSG00000177889 UBE2N o--a
ENSG00000244687 UBE2V1 oo-