PEACHi
GeneSet hsa-let-7b-5p_targets (TarBase_6beta.gmt.txt) is enriched in the following clusters
Cluster log(P) Qvalue Observed in Background Observed in Cluster Expected in Cluster
o--a -3.6 0.01523 245.0 54.0 34.8
Gene expression pattern
Figure: Temporal expression patterns were grouped into clusters with differential expression profiles at three phases of the viral life cycle, namely reverse transcription, integration, and late phase. Boxplots on the left show the distribution of the normalized regression weights for each viral phase used in clustering. Expression change pattern of each gene over time is plotted for mock and HIV samples (dotted orange lines) along with the cluster median (bold red line).
List of genes
Ensembl ID Name Cluster
ENSG00000108825 AARSD1 -o-
ENSG00000135776 ABCB10 o++b
ENSG00000132142 ACACA o--b
ENSG00000151726 ACSL1 NonAssociatedWithProgression
ENSG00000162688 AGL -+o
ENSG00000153207 AHCTF1 o--b
ENSG00000105127 AKAP8 NonAssociatedWithProgression
ENSG00000117448 AKR1A1 ---
ENSG00000214160 ALG3 o--a
ENSG00000153107 ANAPC1 o--a
ENSG00000163516 ANKZF1 ---
ENSG00000143401 ANP32E oo-
ENSG00000198931 APRT o--b
ENSG00000095139 ARCN1 o-o
ENSG00000132254 ARFIP2 ---
ENSG00000140750 ARHGAP17 o+o
ENSG00000185305 ARL15 o++b
ENSG00000112249 ASCC3 NonAssociatedWithProgression
ENSG00000160072 ATAD3B o--a
ENSG00000168397 ATG4B o--b
ENSG00000198925 ATG9A o--a
ENSG00000174437 ATP2A2 -o-
ENSG00000033627 ATP6V0A1 ---
ENSG00000128524 ATP6V1F o--a
ENSG00000087586 AURKA +-o
ENSG00000178999 AURKB o--b
ENSG00000166170 BAG5 NonAssociatedWithProgression
ENSG00000204469 BAT2 ---
ENSG00000198604 BAZ1A NonAssociatedWithProgression
ENSG00000009954 BAZ1B oo-
ENSG00000136261 BZW2 NonAssociatedWithProgression
ENSG00000133678 C10orf57 -+o
ENSG00000138614 C15orf44 o-o
ENSG00000057757 C1orf128 NonAssociatedWithProgression
ENSG00000157181 C1orf27 -+o
ENSG00000125871 C20orf72 NonAssociatedWithProgression
ENSG00000213699 C2orf18 NonAssociatedWithProgression
ENSG00000003509 C2orf56 NonAssociatedWithProgression
ENSG00000235173 C8orf30A ---
ENSG00000136436 CALCOCO2 NonAssociatedWithProgression
ENSG00000153048 CARHSP1 o--b
ENSG00000137944 CCBL2 o-o
ENSG00000136710 CCDC115 o--a
ENSG00000090061 CCNK +-o
ENSG00000108100 CCNY o--b
ENSG00000134690 CDCA8 o--a
ENSG00000103502 CDIPT NonAssociatedWithProgression
ENSG00000145996 CDKAL1 -oo
ENSG00000125817 CENPB o--b
ENSG00000166582 CENPV o--a
ENSG00000167670 CHAF1A o--b
ENSG00000153922 CHD1 o--b
ENSG00000170004 CHD3 o--a
ENSG00000111642 CHD4 o--b
ENSG00000130724 CHMP2A o--a
ENSG00000104472 CHRAC1 NonAssociatedWithProgression
ENSG00000144021 CIAO1 -+o
ENSG00000166855 CLPX NonAssociatedWithProgression
ENSG00000187118 CMC1 -+o
ENSG00000121058 COIL +-o
ENSG00000110442 COMMD9 +-o
ENSG00000181789 COPG NonAssociatedWithProgression
ENSG00000166200 COPS2 o--b
ENSG00000131174 COX7B o+o
ENSG00000071894 CPSF1 o--a
ENSG00000127054 CPSF3L ---
ENSG00000099942 CRKL o--b
ENSG00000062485 CS +-o
ENSG00000141551 CSNK1D o--a
ENSG00000171793 CTPS o-o
ENSG00000055130 CUL1 o++a
ENSG00000036257 CUL3 o--a
ENSG00000179958 DCTPP1 o--a
ENSG00000178105 DDX10 +o+
ENSG00000165732 DDX21 -o-
ENSG00000182810 DDX28 NonAssociatedWithProgression
ENSG00000183258 DDX41 o--a
ENSG00000105671 DDX49 o-o
ENSG00000204560 DHX16 NonAssociatedWithProgression
ENSG00000005100 DHX33 o--a
ENSG00000131504 DIAPH1 o--b
ENSG00000150768 DLAT NonAssociatedWithProgression
ENSG00000136770 DNAJC1 NonAssociatedWithProgression
ENSG00000007923 DNAJC11 o--a
ENSG00000197959 DNM3 o++b
ENSG00000147459 DOCK5 o++b
ENSG00000133884 DPF2 o-o
ENSG00000108591 DRG2 o--b
ENSG00000046604 DSG2 NonAssociatedWithProgression
ENSG00000096696 DSP NonAssociatedWithProgression
ENSG00000081721 DUSP12 NonAssociatedWithProgression
ENSG00000116406 EDEM3 o--a
ENSG00000124802 EEF1E1 NonAssociatedWithProgression
ENSG00000070785 EIF2B3 NonAssociatedWithProgression
ENSG00000161960 EIF4A1 -o-
ENSG00000156976 EIF4A2 o+o
ENSG00000110321 EIF4G2 o+-
ENSG00000066322 ELOVL1 ---
ENSG00000082805 ERC1 o--a
ENSG00000087502 ERGIC2 NonAssociatedWithProgression
ENSG00000125991 ERGIC3 ---
ENSG00000197930 ERO1L ---
ENSG00000134824 FADS2 NonAssociatedWithProgression
ENSG00000153310 FAM49B o+o
ENSG00000166797 FAM96A o++a
ENSG00000160688 FLAD1 o--b
ENSG00000102531 FNDC3A o+o
ENSG00000164916 FOXK1 +-o
ENSG00000143641 GALNT2 o--a
ENSG00000165219 GAPVD1 NonAssociatedWithProgression
ENSG00000006007 GDE1 o--a
ENSG00000082516 GEMIN5 NonAssociatedWithProgression
ENSG00000142252 GEMIN7 o--b
ENSG00000164347 GFM2 NonAssociatedWithProgression
ENSG00000006625 GGCT NonAssociatedWithProgression
ENSG00000170266 GLB1 NonAssociatedWithProgression
ENSG00000124767 GLO1 o-o
ENSG00000160818 GPATCH4 NonAssociatedWithProgression
ENSG00000164284 GRPEL2 o-o
ENSG00000103342 GSPT1 NonAssociatedWithProgression
ENSG00000104687 GSR ---
ENSG00000125484 GTF3C4 NonAssociatedWithProgression
ENSG00000130299 GTPBP3 NonAssociatedWithProgression
ENSG00000104812 GYS1 o--a
ENSG00000164818 HEATR2 o+-
ENSG00000119969 HELLS +o+
ENSG00000137309 HMGA1 o--b
ENSG00000153936 HS2ST1 +o+
ENSG00000067064 IDI1 +-o
ENSG00000006652 IFRD1 NonAssociatedWithProgression
ENSG00000073792 IGF2BP2 -oo
ENSG00000136231 IGF2BP3 o-+
ENSG00000143061 IGSF3 o++a
ENSG00000106348 IMPDH1 o--a
ENSG00000178035 IMPDH2 o-o
ENSG00000165458 INPPL1 ---
ENSG00000185085 INTS5 o--b
ENSG00000143493 INTS7 +oo
ENSG00000196497 IPO4 o--b
ENSG00000133704 IPO8 NonAssociatedWithProgression
ENSG00000178695 KCTD12 o++b
ENSG00000102763 KIAA0564 o+o
ENSG00000132361 KIAA0664 ---
ENSG00000134313 KIDINS220 -+o
ENSG00000068796 KIF2A o+o
ENSG00000143815 LBR +oo
ENSG00000139233 LLPH o--a
ENSG00000111684 LPCAT3 o--a
ENSG00000123684 LPGAT1 o++b
ENSG00000066557 LRRC40 o+o
ENSG00000130764 LRRC47 NonAssociatedWithProgression
ENSG00000136802 LRRC8A +oo
ENSG00000041802 LSG1 -o-
ENSG00000164167 LSM6 NonAssociatedWithProgression
ENSG00000162441 LZIC NonAssociatedWithProgression
ENSG00000126934 MAP2K2 o--a
ENSG00000116871 MAP7D1 o-o
ENSG00000166986 MARS o--b
ENSG00000152428 MARS2 NonAssociatedWithProgression
ENSG00000038274 MAT2B o+o
ENSG00000100294 MCAT o--b
ENSG00000164654 MIOS o++b
ENSG00000027001 MIPEP -oo
ENSG00000075975 MKRN2 NonAssociatedWithProgression
ENSG00000173542 MOBKL1A NonAssociatedWithProgression
ENSG00000114978 MOBKL1B -+o
ENSG00000103152 MPG o--a
ENSG00000129282 MRM1 ---
ENSG00000136522 MRPL47 o--a
ENSG00000239789 MRPS17 NonAssociatedWithProgression
ENSG00000062582 MRPS24 o--a
ENSG00000090263 MRPS33 --o
ENSG00000105887 MTPN NonAssociatedWithProgression
ENSG00000124275 MTRR o+-
ENSG00000214114 MYCBP -oo
ENSG00000145414 NAF1 o--a
ENSG00000137513 NARS2 NonAssociatedWithProgression
ENSG00000146918 NCAPG2 NonAssociatedWithProgression
ENSG00000069869 NEDD4 -+o
ENSG00000244005 NFS1 NonAssociatedWithProgression
ENSG00000164190 NIPBL NonAssociatedWithProgression
ENSG00000073536 NLE1 o--b
ENSG00000165271 NOL6 o--b
ENSG00000166197 NOLC1 o--b
ENSG00000087269 NOP14 o--a
ENSG00000213281 NRAS o--b
ENSG00000107672 NSMCE4A o+o
ENSG00000095906 NUBP2 o--a
ENSG00000213965 NUDT19 o++a
ENSG00000113569 NUP155 NonAssociatedWithProgression
ENSG00000126883 NUP214 NonAssociatedWithProgression
ENSG00000163002 NUP35 oo-
ENSG00000143748 NVL NonAssociatedWithProgression
ENSG00000167693 NXN ---
ENSG00000155463 OXA1L +o+
ENSG00000154814 OXNAD1 +o+
ENSG00000175575 PAAF1 o--a
ENSG00000079462 PAFAH1B3 o--a
ENSG00000138801 PAPSS1 -+o
ENSG00000114054 PCCB NonAssociatedWithProgression
ENSG00000161217 PCYT1A NonAssociatedWithProgression
ENSG00000114209 PDCD10 NonAssociatedWithProgression
ENSG00000148843 PDCD11 NonAssociatedWithProgression
ENSG00000174840 PDE12 NonAssociatedWithProgression
ENSG00000110435 PDHX o+o
ENSG00000152256 PDK1 NonAssociatedWithProgression
ENSG00000013375 PGM3 +o+
ENSG00000101856 PGRMC1 o-o
ENSG00000104872 PIH1D1 o-o
ENSG00000160783 PMF1 o-o
ENSG00000106628 POLD2 o--b
ENSG00000068654 POLR1A NonAssociatedWithProgression
ENSG00000125630 POLR1B oo-
ENSG00000102978 POLR2C NonAssociatedWithProgression
ENSG00000163882 POLR2H o-o
ENSG00000177700 POLR2L o-o
ENSG00000013503 POLR3B -+o
ENSG00000196313 POM121 o--b
ENSG00000104356 POP1 o+o
ENSG00000171497 PPID o--b
ENSG00000115241 PPM1G o--a
ENSG00000115685 PPP1R7 o--a
ENSG00000198056 PRIM1 ---
ENSG00000147224 PRPS1 o--a
ENSG00000110801 PSMD9 o--b
ENSG00000131467 PSME3 o-o
ENSG00000134644 PUM1 o--a
ENSG00000177192 PUS1 NonAssociatedWithProgression
ENSG00000172053 QARS o--b
ENSG00000130348 QRSL1 -+o
ENSG00000118873 RAB3GAP2 ---
ENSG00000137040 RANBP6 o--a
ENSG00000123728 RAP2C o++b
ENSG00000183808 RBM12B o+o
ENSG00000188739 RBM34 NonAssociatedWithProgression
ENSG00000121039 RDH10 NonAssociatedWithProgression
ENSG00000137710 RDX NonAssociatedWithProgression
ENSG00000168476 REEP4 o-+
ENSG00000143878 RHOB +-o
ENSG00000177105 RHOG o--a
ENSG00000058729 RIOK2 ---
ENSG00000103549 RNF40 o--a
ENSG00000101654 RNMT NonAssociatedWithProgression
ENSG00000171861 RNMTL1 ---
ENSG00000152464 RPP38 o+o
ENSG00000171848 RRM2 o--a
ENSG00000137996 RTCD1 NonAssociatedWithProgression
ENSG00000085365 SCAMP1 NonAssociatedWithProgression
ENSG00000099194 SCD +-o
ENSG00000136193 SCRN1 --o
ENSG00000142186 SCYL1 -o-
ENSG00000198301 SDAD1 o--a
ENSG00000140612 SEC11A oo-
ENSG00000148396 SEC16A ---
ENSG00000101310 SEC23B NonAssociatedWithProgression
ENSG00000156304 SFRS15 ---
ENSG00000097033 SH3GLB1 o+o
ENSG00000147955 SIGMAR1 ---
ENSG00000115902 SLC1A4 NonAssociatedWithProgression
ENSG00000115840 SLC25A12 o++a
ENSG00000004864 SLC25A13 NonAssociatedWithProgression
ENSG00000125454 SLC25A19 o--a
ENSG00000085491 SLC25A24 o++b
ENSG00000164933 SLC25A32 +-o
ENSG00000170385 SLC30A1 o-o
ENSG00000162695 SLC30A7 o+o
ENSG00000111371 SLC38A1 +-o
ENSG00000134294 SLC38A2 oo-
ENSG00000017483 SLC38A5 ---
ENSG00000109062 SLC9A3R1 o--a
ENSG00000127616 SMARCA4 o--b
ENSG00000173473 SMARCC1 o--a
ENSG00000066117 SMARCD1 NonAssociatedWithProgression
ENSG00000092531 SNAP23 o+o
ENSG00000067066 SP100 o++b
ENSG00000129128 SPCS3 ---
ENSG00000116096 SPR ---
ENSG00000131018 SYNE1 o++b
ENSG00000108639 SYNGR2 o--a
ENSG00000085231 TAF9 o+o
ENSG00000187325 TAF9B o--b
ENSG00000121749 TBC1D15 o+o
ENSG00000136270 TBRG4 o--a
ENSG00000070814 TCOF1 o--b
ENSG00000138297 TIMM23 o--a
ENSG00000126953 TIMM8A NonAssociatedWithProgression
ENSG00000100575 TIMM9 -+o
ENSG00000117500 TMED5 o+o
ENSG00000174695 TMEM167A o+-
ENSG00000135048 TMEM2 NonAssociatedWithProgression
ENSG00000188807 TMEM201 o--a
ENSG00000109133 TMEM33 -+o
ENSG00000164983 TMEM65 NonAssociatedWithProgression
ENSG00000127774 TMEM93 oo+
ENSG00000139324 TMTC3 o++b
ENSG00000132773 TOE1 ---
ENSG00000134900 TPP2 o+o
ENSG00000170638 TRABD ---
ENSG00000122779 TRIM24 NonAssociatedWithProgression
ENSG00000153827 TRIP12 NonAssociatedWithProgression
ENSG00000072756 TRNT1 o++a
ENSG00000116747 TROVE2 NonAssociatedWithProgression
ENSG00000167112 TRUB2 o--a
ENSG00000162222 TTC9C o++b
ENSG00000100304 TTLL12 o--a
ENSG00000176890 TYMS NonAssociatedWithProgression
ENSG00000144744 UBA3 o++b
ENSG00000143569 UBAP2L o--b
ENSG00000131508 UBE2D2 --o
ENSG00000109332 UBE2D3 NonAssociatedWithProgression
ENSG00000103275 UBE2I o--a
ENSG00000104691 UBXN8 o+o
ENSG00000143179 UCK2 +o+
ENSG00000174607 UGT8 NonAssociatedWithProgression
ENSG00000034063 UHRF1 o--b
ENSG00000092929 UNC13D ---
ENSG00000138768 USO1 NonAssociatedWithProgression
ENSG00000103194 USP10 NonAssociatedWithProgression
ENSG00000135655 USP15 NonAssociatedWithProgression
ENSG00000164338 UTP15 -o-
ENSG00000108651 UTP6 NonAssociatedWithProgression
ENSG00000049245 VAMP3 NonAssociatedWithProgression
ENSG00000115561 VPS24 NonAssociatedWithProgression
ENSG00000166887 VPS39 NonAssociatedWithProgression
ENSG00000116874 WARS2 o-o
ENSG00000174374 WBSCR16 ---
ENSG00000136709 WDR33 +o+
ENSG00000160193 WDR4 o--a
ENSG00000133316 WDR74 o--b
ENSG00000115368 WDR75 NonAssociatedWithProgression
ENSG00000124571 XPO5 o+o
ENSG00000130227 XPO7 o--b
ENSG00000114127 XRN1 o++b
ENSG00000058673 ZC3H11A NonAssociatedWithProgression